Aug 05, 2021  
2011-2012 University Catalog 
2011-2012 University Catalog [ARCHIVED CATALOG]

Pharmacology and Toxicology – MS and PhD

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Programs of advanced study and laboratory research in the disciplines of pharmacology and toxicology, leading to the master of science and doctor of philosophy degrees, are intended to prepare qualified students for professional careers as pharmacologists or toxicologists in academia, private industry, or public service. Graduate coursework emphasizes integration of biochemistry, cell and molecular biology, physiology, pharmacology, toxicology, statistics, and experimental design. Theory and methodologic aspects are considered within the context of current research literature in these fields. At least 20 didactic credits of graduate coursework (700 and 800 level) are required for either degree. Students propose, develop, and perform an independent research project under the guidance of a faculty advisory committee and defend their master’s or doctoral thesis before an examination committee of graduate faculty and other expert scientists. Predoctoral students must pass written and oral comprehensive qualifying exams. Publication of research results in peer-reviewed journals is expected. Current research interests of the pharmacology and toxicology faculty encompass cancer pharmacology; metabolism and cellular mechanisms of toxicity of drugs and xenobiotics; cancer cell motility and signaling; and cardiovascular- and neuropharmacology.

Program Requirements

All or most of the didactic coursework is completed within the first two years.


Bin Chen
BS, MS (Nanjing, China); PhD (Catholic University, Leuven, Belgium)
Associate Professor of Pharmaceutical Sciences
Director, Graduate Program in Pharmacology and Toxicology
Phone: 215.596.7481
Research: effects and mechanisms of photodynamic tumor vascular targeting; synthesis and evaluation of novel optical molecular probes for tumor imaging and targeting.

Adeboye Adejare
BS, MS (Iowa); PhD (Ohio State) 
Professor of Pharmaceutical Sciences
Phone: 215.596.8944
Research: mechanisms of neurodegeneration; drug targeting; pharmaceutical profiling; chemistry of fluoroaromatic compounds

Russell J. DiGate
BA, MS, PhD (University of Rochester)
Professor of Pharmaceutical Sciences
Phone: 215.596.8805
Research: role of DNA helicases and topoisomerases in DNA metabolism; design and synthesis of novel antibiotics that target DNA topoisomerases

Peter J. Harvison
BS (Carnegie Mellon); PhD (SUNY, Buffalo) 
Abramson Chair of Pharmacology and Toxicology
Phone: 215.596.8979
Research: metabolism of drugs and environmental chemicals in vivo and in vitro; role of glutathione in toxication and detoxication

Zhiyu Li
BS (Nakai, China); MS (Science and Technology, China);
PhD (Maryland) 
Assistant Professor of Pharmaceutical Sciences
Phone: 215.596.8943
Research: design and engineering protein-based carriers for drug formulation, targeting, and delivery; protein and nucleic acid drug delivery

Catherine C. Moore
BA (Colgate); PhD (Pennsylvania)
Assistant Professor of Pharmacology and Toxicology 
Phone: 267.295.3180
Research: regulation of G protein-coupled receptors in cancer cells; biochemical mechanisms of tumor metastasis involving monomeric G proteins

Diane W. Morel
BA (Douglass); MS, PhD (Case Western Reserve)
Associate Professor of Pharmacology and Toxicology
Director, BS Pharmacology and Toxicology Program
Assistant Dean, Curriculum and Assessment, Philadelphia College of Pharmacy
Phone: 215.895.1123
Research: oxidized lipids/lipoproteins in chronic disease states; vascular cell function/disfunction; cardiovascular toxicology

Raymond F. Orzechowski
BS (Philadelphia College of Pharmacy and Science); MS, PhD (Temple)
Professor Emeritus of Pharmacology and Toxicology

Joan B. Tarloff
BS, MS (Toledo); PhD (Medical College of Ohio)
Professor of Pharmacology and Toxicology
Interim Chair, Department of Pharmaceutical Sciences
Phone: 215.596.8983
Research: renal pharmacology and toxicology; correlation of in vivo and in vitro expressions of toxicant-induced injury

Ruy Tchao
BS (Nottingham, England); PhD (Manchester, England)
Professor of Pharmacology and Toxicology
Phone: 215.596.8978
Research: extracellular matrix molecules and effects of pharmacologic agents on cancer-cell motility and invasion: in vitro toxicity assays with epithelial cell lines

Shanaz M. Tejani-Butt
BS, MS (Bombay); PhD (Medical College of Virginia)
Professor of Pharmacology and Toxicology
Associate Dean, College of Graduate Studies
Phone: 215.596.8594
Research: molecular mechanisms associated with regulation of biogenic amine transporters; the role of these systems in modulating stress responses; therapeutic actions of psychoactive agents in psychiatric disorders

Adjunct Faculty

David Cragin
PhD (University of California)
Adjunct Associate Professor of Pharmacology and Toxicology

Lynn Flowers
PhD (West Virginia University)
Adjunct Associate Professor of Pharmacology and Toxicology

Matthew V. Lorenzi
BS (Marquette); PhD (Miami)
Adjunct Associate Professor

Steve J. Offord
Adjunct Associate Professor of Pharmacology and Toxicology

William Pare
PhD (Carnegie Mellon); PhD (Delaware)
Adjunct Professor of Pharmacology and Toxicology

Thomas H. Rushmore
BSc (Muhlenberg); MSc (Fairleigh Dickinson);
PhD (Thomas Jefferson)
Adjunct Associate Professor

Barry Sachais
BS (Rutgers); PhD (New Jersey College of Medicine)
Adjunct Associate Professor

Lindon Young
BA (Immaculate); PhD (USciences)
Adjunct Assistant Professor

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